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  1. The cell proliferative markers are very important in breast cancer. Since SPAG5 and NuMA proteins play a significant role in the mitosis regulatory network and cell division, we aimed to study their mRNA level...

    Authors: Zeinab Mohamadalizadeh-Hanjani, Shirin Shahbazi and Loabat Geranpayeh

    Citation: World Journal of Surgical Oncology 2020 18:225

    Content type: Research

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  2. Although RNA-binding proteins play an essential role in a variety of different tumours, there are still limited efforts made to systematically analyse the role of RNA-binding proteins (RBPs) in the survival of...

    Authors: Xuehui Fan, Lili Liu, Yue Shi, Fanghan Guo, Haining Wang, Xiuli Zhao, Di Zhong and Guozhong Li

    Citation: World Journal of Surgical Oncology 2020 18:222

    Content type: Research

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  3. Sarcopenia is a prognostic factor in various cancers. However, the impact of sarcopenia in patients with recurrent pancreatic cancer remains unclear. This study evaluated the prognostic significance of sarcope...

    Authors: Teruhisa Sakamoto, Takuki Yagyu, Ei Uchinaka, Kozo Miyatani, Takehiko Hanaki, Kyoichi Kihara, Tomoyuki Matsunaga, Manabu Yamamoto, Naruo Tokuyasu, Soichiro Honjo and Yoshiyuki Fujiwara

    Citation: World Journal of Surgical Oncology 2020 18:221

    Content type: Research

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  5. Hepatocellular carcinoma (HCC) is the most common malignant tumor of the liver, and its morbidity and mortality have been increasing in recent years. The early diagnosis and prompt treatment of small HCC are c...

    Authors: Xue-Qin Li, Xing Wang, Da-Wei Zhao, Jun Sun, Jiao-Jiao Liu, Dong-Dong Lin, Guang Yang, Hui Liu, Zhen-Ying Xia, Cui-Yu Jia and Hong-Jun Li

    Citation: World Journal of Surgical Oncology 2020 18:219

    Content type: Review

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  6. Adenocarcinoma of the pancreatic body and tail is associated with a dismal prognosis. As patients frequently present themselves with locally advanced tumors, extended surgery including multivisceral resection ...

    Authors: Oliver Beetz, Akin Sarisin, Alexander Kaltenborn, Jürgen Klempnauer, Michael Winkler and Gerrit Grannas

    Citation: World Journal of Surgical Oncology 2020 18:218

    Content type: Research

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  8. Transurethral resection of the bladder tumour (TUR) is associated with a risk of bladder perforation. The underlying mechanisms and risk factors are not fully understood. The aim of this study was to determine...

    Authors: Sławomir Poletajew, Tomasz Ilczuk, Wojciech Krajewski, Grzegorz Niemczyk, Agata Cyran, Łukasz Białek, Piotr Radziszewski, Barbara Górnicka and Piotr Kryst

    Citation: World Journal of Surgical Oncology 2020 18:216

    Content type: Research

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  9. Natural orifice specimen extraction surgery is a novel technique of minimally invasive surgery. The purpose of this study was to compare the safety of laparoscopic anterior resection with natural orifice speci...

    Authors: Jun He, Hai-Bo Yao, Chang-Jian Wang, Qin-Yan Yang, Jian-Ming Qiu, Jin-Ming Chen, Zhong Shen and Guan-Gen Yang

    Citation: World Journal of Surgical Oncology 2020 18:215

    Content type: Research

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  10. Recently, a novel surgical procedure, named as laparoscopic proximal gastrectomy (LPG) with double-tract reconstruction (DTR), has been reported to provide surgical benefits in the treatment of proximal early ...

    Authors: Yixin Xu, Jie Gao, Yibo Wang, Yulin Tan, Cheng Xi, Nianyuan Ye, Dapeng Wu and Xuezhong Xu

    Citation: World Journal of Surgical Oncology 2020 18:214

    Content type: Review

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  11. Lymph node staging of ductal adenocarcinoma of the pancreatic head (PDAC) by cross-sectional imaging is limited. The aim of this study was to determine the diagnostic accuracy of expanded criteria in nodal sta...

    Authors: Florian N. Loch, Patrick Asbach, Matthias Haas, Hendrik Seeliger, Katharina Beyer, Christian Schineis, Claudius E. Degro, Georgios A. Margonis, Martin E. Kreis and Carsten Kamphues

    Citation: World Journal of Surgical Oncology 2020 18:213

    Content type: Research

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  12. Laparoscopic tumor-specific mesorectal excision (TSME) preserving the left colic artery and superior rectal artery is still a technically challenging procedure. We conducted this study to demonstrate the feasi...

    Authors: Chi Zhang, Hao-tang Wei, Wenqing Hu, Yueming Sun, Qinyuan Zhang, Masanobu Abe, Zhuoran Du, Yingying Xu, Liang Zong and Xiang Hu

    Citation: World Journal of Surgical Oncology 2020 18:212

    Content type: Research

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  13. Cowden’s syndrome is an autosomal dominant disease with variable penetrance, involving the tumor suppressor phosphatase and tension homolog gene, located on chromosome 10q22-23, responsible for cell proliferat...

    Authors: Sofia Miguelote, Roberto Silva, J. L. Fougo, L. E. Barbosa and J. P. Araújo Teixeira

    Citation: World Journal of Surgical Oncology 2020 18:211

    Content type: Case report

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  14. Ischemia–reperfusion injury is harmful in partial nephrectomy (PN) in renal cell carcinoma. Choosing an appropriate surgical method is important to reduce ischemia–reperfusion injury. This study aimed to compa...

    Authors: Jinhong Xu, Shuxiong Xu, Biao Yao, Run Xu, Yuangao Xu, Fa Sun, Qian Qiu and Hua Shi

    Citation: World Journal of Surgical Oncology 2020 18:210

    Content type: Research

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  15. Angiopoietin-Tie2 and nitric oxide pathway is crucial in tumor angiogenesis and closely correlates with tumor development, growth, and metastasis. This study aimed to investigate the angiopoietin-Tie2 and nitr...

    Authors: Hsiang-Ling Wu, You-Hsiang Chu, Ying-Hsuan Tai, Mei-Yung Tsou, Cheng-Hsien Wu, Wen-Liang Lo, Shyh-Kuan Tai, Chun-Chang Yeh and Chih-Cherng Lu

    Citation: World Journal of Surgical Oncology 2020 18:209

    Content type: Research

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  16. Pancreatic neuroendocrine tumors (PNET) are rare, with a significant malignant potential. This study aimed to determine outcomes of patients with resected PNETs according to the cystic component and confirm th...

    Authors: Ange Khalil, Jacques Ewald, Ugo Marchese, Aurélie Autret, Jonathan Garnier, Patricia Niccoli, Gilles Piana, Flora Poizat, Marc Giovannini, Jean-Robert Delpero and Olivier Turrini

    Citation: World Journal of Surgical Oncology 2020 18:208

    Content type: Research

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  17. One of the most severe complications of low anterior rectal resection is anastomotic leakage (AL). The creation of a loop ileostomy (LI) reduces the prevalence of AL requiring surgical intervention. However, u...

    Authors: Marcin Zeman, Marek Czarnecki, Andrzej Chmielarz, Adam Idasiak, Maciej Grajek and Agnieszka Czarniecka

    Citation: World Journal of Surgical Oncology 2020 18:207

    Content type: Research

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  18. The role of renal artery embolization (RAE) in the therapeutic armamentarium is always controversial. The present study aimed to assess the safety and the surgical outcomes of the instant renal artery emboliza...

    Authors: Guangxin Tang, Xiaoxu Chen, Jianwei Wang, Wei He and Zhihong Niu

    Citation: World Journal of Surgical Oncology 2020 18:206

    Content type: Research

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  19. Anastomotic leakage (AL) significantly impairs short-term outcomes. The impact on the long-term outcomes remains unclear. This study aimed to identify the risk factors for AL and the impact on long-term surviv...

    Authors: Marius Kryzauskas, Augustinas Bausys, Austeja Elzbieta Degutyte, Vilius Abeciunas, Eligijus Poskus, Rimantas Bausys, Audrius Dulskas, Kestutis Strupas and Tomas Poskus

    Citation: World Journal of Surgical Oncology 2020 18:205

    Content type: Research

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  20. Due to the controversy over the prognostic significance of Borrmann type in patients with gastric cancer (GC), the present study was to investigate the clinical value of Borrmann type in advanced GC.

    Authors: Xiao-Hai Song, Wei-Han Zhang, Kai-Liu, Xiao-Long Chen, Lin-Yong Zhao, Xin-Zu Chen, Kun-Yang, Zong-Guang Zhou and Jian-Kun Hu

    Citation: World Journal of Surgical Oncology 2020 18:204

    Content type: Research

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  21. Morphologically, osteofibrous dysplasia-like adamantinoma is thought to be intermediate between osteofibrous dysplasia and adamantinoma. Its treatment is not well established owing to its rarity.

    Authors: Yuji Yamamura, Makoto Emori, Nobuyuki Takahashi, Mitsumasa Chiba, Junya Shimizu, Yasutaka Murahashi, Shintaro Sugita, Kousuke Iba, Tadashi Hasegawa and Toshihiko Yamashita

    Citation: World Journal of Surgical Oncology 2020 18:203

    Content type: Case report

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  22. Thymic epithelial tumors are rare neoplasias. There are no internationally accepted standards to treat this complex oncological disease. The studies on which our knowledge is based frequently have methodologic...

    Authors: Marius Kemper, Mona Moradzadeh, Eugen Bellon, Ahmad S. Bahar, Rainer Grotelüschen, Matthias Reeh, Jakob R. Izbicki and Kai Bachmann

    Citation: World Journal of Surgical Oncology 2020 18:202

    Content type: Research

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  23. To estimate the prognostic value of positive surgical margins (PSM) location and perineural invasion (PNI) for biochemical recurrence (BCR) in patients undergoing radical prostatectomy (RP).

    Authors: Zhenpeng Lian, Hongtuan Zhang, Zhaowei He, Shenfei Ma, Xiaoming Wang and Ranlu Liu

    Citation: World Journal of Surgical Oncology 2020 18:201

    Content type: Research

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  24. Recent phase III randomized trials have suggested that neoadjuvant chemotherapy followed by interval debulking surgery (NACT-IDS) is a treatment option for patients with advanced epithelial ovarian cancer. Thi...

    Authors: Kazuto Nakamura, Yoshikazu Kitahara, Toshio Nishimura, Soichi Yamashita, Keiko Kigure, Ikuro Ito and Tatsuya Kanuma

    Citation: World Journal of Surgical Oncology 2020 18:200

    Content type: Research

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  25. Several randomized controlled trials (RCTs) compared the effects of laparoscopic hepatectomy (LH) and radiofrequency ablation (RFA) for the treatment of hepatocellular carcinoma (HCC), but the results have rem...

    Authors: Shan Jin, Shisheng Tan, Wen Peng, Ying Jiang and Chunshan Luo

    Citation: World Journal of Surgical Oncology 2020 18:199

    Content type: Review

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  26. To assess the feasibility and short-term outcomes of neoadjuvant chemoradiotherapy (CCRT) followed by transanal total mesorectal excision assisted by single-port laparoscopic surgery (TaTME-SPLS) for low-lying...

    Authors: Yen-Jung Lu, Chien-Hsin Chen, En-Kwang Lin and Szu-Yuan Wu

    Citation: World Journal of Surgical Oncology 2020 18:198

    Content type: Research

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  27. Systemic immune-inflammation index (SII) has been suggested to be effective to reflect the inflammatory status and thus may be an underlying biomarker for prognosis prediction. This hypothesis has been demonst...

    Authors: Yongfang Ji and Haiyan Wang

    Citation: World Journal of Surgical Oncology 2020 18:197

    Content type: Review

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  28. Patients with stage II deficient mismatch repair (dMMR) show a better prognosis than patients with colorectal cancer (CRC) with proficient mismatch repair (pMMR). However, this beneficial effect is decreased i...

    Authors: Bingyan Wang, Fei Li, Limei Guo, Siyi Lu, Junren Ma, Yanpeng Ma, Yan Meng, Junwei Wang, Xin Zhou and Wei Fu

    Citation: World Journal of Surgical Oncology 2020 18:196

    Content type: Research

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  29. Although hereditary non-polyposis colorectal cancer (HNPCC) could be subtyped into proficient or deficient mismatch repair gene expression (pMMR or dMMR), distinct clinical features between these two subgroups...

    Authors: Ci-Yuan Sun, Jy-Ming Chiang, Tse-Ching Chen, Hsin-Yun Hung and Jeng-Fu You

    Citation: World Journal of Surgical Oncology 2020 18:195

    Content type: Research

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  30. Frailty results in a high risk for disability, hospitalization, and mortality. This study aimed to investigate perioperative details of frail patients who underwent pancreatectomy and whether frailty can be a ...

    Authors: Yutaka Nakano, Yuki Hirata, Tatsuya Shimogawara, Toru Yamada, Koki Mihara, Ryo Nishiyama, Shin Nishiya, Hideki Taniguchi and Tomohisa Egawa

    Citation: World Journal of Surgical Oncology 2020 18:194

    Content type: Research

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  31. The impact of primary tumor resection (PTR) on the prognosis of unresectable metastatic colorectal cancer (mCRC) patients remains debatable. We aimed to develop several prognostic nomograms which could be usef...

    Authors: Yi Yang, Yujie Lu, Wen Jiang, Jinzhou Zhu and Su Yan

    Citation: World Journal of Surgical Oncology 2020 18:193

    Content type: Research

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  32. Several studies have reported the Cyclooxygenase 2 (COX-2) rs689466 polymorphism as a susceptibility locus of colorectal cancer (CRC), but their findings are inconsistent. Thus, this meta-analysis was performe...

    Authors: Yong-Chen Zhang, Hui Zhao, Chen Chen and Mohammad Amzad Ali

    Citation: World Journal of Surgical Oncology 2020 18:192

    Content type: Research

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  33. Pre-treatment PLR (platelet-lymphocyte ratio) was reported to be associated with the prognosis in gastric cancer (GC), but the results remain inconclusive. This meta-analysis aimed to investigate the prognosti...

    Authors: Xunlei Zhang, Wenjing Zhao, Yang Yu, Xue Qi, Li Song, Chenfei Zhang, Guoxing Li and Lei Yang

    Citation: World Journal of Surgical Oncology 2020 18:191

    Content type: Research

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  34. Colorectal cancer resection surgery with transvaginal specimen extraction is becoming increasingly accepted and used by surgeons. However, few publications on robotic anterior sigmoid colon and rectal cancer r...

    Authors: Gengmei Gao, Lan Chen, Rui Luo, Bo Tang and Taiyuan Li

    Citation: World Journal of Surgical Oncology 2020 18:190

    Content type: Research

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  35. Hepatocellular carcinoma (HCC) is a malignant tumor with frequent intrahepatic metastases; extrahepatic metastases are not rare but less frequent compared to intrahepatic ones. The most frequent sites of extra...

    Authors: Yong-Ming Yu, Yi-Sheng Cao, Zhou Wu, Rong Huang and Zhong-Lei Shen

    Citation: World Journal of Surgical Oncology 2020 18:189

    Content type: Case report

    Published on:

  36. Lateral lymph node metastasis (LLNM) is very common in papillary thyroid carcinoma (PTC). The influence of tumour location on LLNM remains controversial. The purpose of this study was to reveal the association...

    Authors: Yi Dou, Daixing Hu, Yingji Chen, Wei Xiong, Qi Xiao and Xinliang Su

    Citation: World Journal of Surgical Oncology 2020 18:188

    Content type: Research

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  37. Neoplastic spinal cord compression is a cause of severe disability in cancer patients. To prevent irreversible paraplegia, a structured strategy is required to address the various impairments present in cancer...

    Authors: Yukako Ishida, Hideki Shigematsu, Shinji Tsukamoto, Yasuhiko Morimoto, Eiichiro Iwata, Akinori Okuda, Sachiko Kawasaki, Masato Tanaka, Hiromasa Fujii, Yasuhito Tanaka and Akira Kido

    Citation: World Journal of Surgical Oncology 2020 18:187

    Content type: Research

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  38. Recently, reports have classified lymphocyte to monocyte ratio (LMR) as an effective indicator for predicting the prognosis of pancreatic cancer. Nevertheless, the prognostic value of LMR for pancreatic cancer...

    Authors: Shuwen Lin, Yinghua Fang, Zhikang Mo, Ye Lin, Chenggang Ji and Zhixiang Jian

    Citation: World Journal of Surgical Oncology 2020 18:186

    Content type: Research

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  39. Tumor size is one of the most important issues for hepatocellular carcinoma (HCC) treatment and prognosis, but the classification of it is still controversial. The aim of this study was to screen appropriate c...

    Authors: Hongzhi Liu, Yuan Yang, Chuanchun Chen, Lei Wang, Qizhen Huang, Jianxing Zeng, Kongying Lin, Yongyi Zeng, Pengfei Guo, Weiping Zhou and Jingfeng Liu

    Citation: World Journal of Surgical Oncology 2020 18:185

    Content type: Research

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  40. Talc pleurodesis (TP) and indwelling pleural catheter (IPC) are used for the management of malignant pleural effusion (MPE). Our meta-analysis was conducted to assess the efficacy and safety of both treatments...

    Authors: Li Wang, Huan Deng, Xinling Chen, Can Li, Fengming Yi, Yiping Wei and Wenxiong Zhang

    Citation: World Journal of Surgical Oncology 2020 18:184

    Content type: Research

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  41. Gastrointestinal stromal tumors (GIST) arising from sites other than the gastrointestinal (GI) tract, termed extra-gastrointestinal stromal tumors (EGIST), are rare. Among EGIST, those with platelet-derived gr...

    Authors: Kohei Kanamori, Yukinori Yamagata, Yoshitaka Honma, Keiichi Date, Takeyuki Wada, Tsutomu Hayashi, Sho Otsuki, Shigeki Sekine, Takaki Yoshikawa, Hitoshi Katai and Toshiro Nishida

    Citation: World Journal of Surgical Oncology 2020 18:183

    Content type: Case report

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  42. Appendiceal and colorectal cancers with peritoneal carcinomatosis (PC) can derive benefit from cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC). However, its role in gastric and ...

    Authors: Natasha Leigh, Daniel Solomon, Eric Pletcher, Daniel M. Labow, Deepa R. Magge, Umut Sarpel and Benjamin J. Golas

    Citation: World Journal of Surgical Oncology 2020 18:182

    Content type: Research

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  43. The purpose of this study is to explore the role and mechanism of MMP-9 in the EMT process of thyroid cancer (TC), so as to provide a basis for clinical exploration of invasion and metastasis process of TC, lo...

    Authors: Yuanchun Li, Jing He, Feng Wang, Xin Wang, Fan Yang, Chunyang Zhao, Chunling Feng and Tiejun Li

    Citation: World Journal of Surgical Oncology 2020 18:181

    Content type: Research

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  44. The purpose of this study is to compare the difference of clinical efficacy between conventional intraperitoneal chemotherapy and HIPEC, so as to explore the clinical application value and advantages of HIPEC.

    Authors: Jie Jiao, Chengzhen Li, Guanying Yu, Lei Zhang, Xiaoyan Shi, Jingdu Yan, Houjun Zhang and Peiming Guo

    Citation: World Journal of Surgical Oncology 2020 18:180

    Content type: Research

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  45. Patients with stage IV gastric cancer have a poor prognosis despite the recent development of multidisciplinary treatments that include chemotherapy. However, conversion surgery has emerged as a promising stra...

    Authors: Ryu Matsumoto, Takaaki Arigami, Daisuke Matsushita, Keishi Okubo, Takako Tanaka, Shigehiro Yanagita, Ken Sasaki, Masahiro Noda, Yoshiaki Kita, Shinichiro Mori, Hiroshi Kurahara and Takao Ohtsuka

    Citation: World Journal of Surgical Oncology 2020 18:179

    Content type: Case report

    Published on:

  46. Sentinel lymph node biopsy (SLNB) plays a vital role in breast cancer surgery, and the identified number of sentinel nodes determines its accuracy for representing the status of the axillae. There are two type...

    Authors: Chenxi Yuan, Xinzhao Wang, Zhaoyun Liu, Chao Li, Mengxue Bian, Jing Shan, Xiang Song, Zhiyong Yu and Jinming Yu

    Citation: World Journal of Surgical Oncology 2020 18:178

    Content type: Research

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  47. We aimed to investigate the usefulness of magnetic resonance imaging (MRI) and histopathological shrinkage patterns to formulate a predictive equation for estimating residual tumor size after neoadjuvant chemo...

    Authors: Katsuhiro Yoshikawa, Mitsuaki Ishida, Naoki Kan, Hirotsugu Yanai, Koji Tsuta, Mitsugu Sekimoto and Tomoharu Sugie

    Citation: World Journal of Surgical Oncology 2020 18:177

    Content type: Research

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  48. Deoxycytidine kinase (DCK), an enzyme in the nucleoside biosynthetic pathway, can affect the development of immune cells. However, the relationships between the expression of DCK, patient prognosis, and tumor-inf...

    Authors: Danjun Song, Yining Wang, Kai Zhu, Lingyu Tian, Qiang Gao, Jian Zhou, Jia Fan and Xiaoying Wang

    Citation: World Journal of Surgical Oncology 2020 18:176

    Content type: Research

    Published on:

  49. Previous randomized controlled trials have compared the efficacy and safety of single chest drain (SCD) and double chest drains (DCD) in the patients undergone pulmonary lobectomy, yet the results remain incon...

    Authors: Jinzhi You, Hailing Zhang, Wei Li, Ninghuang Dai and Zhongfeng Zheng

    Citation: World Journal of Surgical Oncology 2020 18:175

    Content type: Research

    Published on:

  50. The effect and safety of preoperative biliary drainage (PBD) in patients with perihilar cholangiocarcinoma are still controversial; the aim of our study is to evaluate all aspects of PBD.

    Authors: Fei Teng, You-yin Tang, Jun-long Dai, Yongkun Li and Zhe-yu Chen

    Citation: World Journal of Surgical Oncology 2020 18:174

    Content type: Research

    Published on:

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