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Table 3 Competing risk analysis of 5-year mortality

From: Survival analysis of extramammary Paget’s disease (EMPD) in a tertiary hospital in Taiwan

Variate Mortality rate Sub-HR 95% CI p-value
Gender
 Female 16.67% Reference Reference Reference
 Male 39.53% 2.737 0.632–11.859 0.1784
Age
 Age less than 75 years old 24.00% Reference Reference Reference
 Age= 75 years old or more 43.33% 2.127 0.808–5.600 0.1265
Lesion site
 Genital region or others 26.32% Reference Reference Reference
 Perianal or perineal region 52.94% 2.338 0.948–5.765 0.0651
Size of lesion
 Lesion = 2 cm or less 26.32% Reference Reference Reference
 Lesion lager than 2 cm 38.89% 1.624 0.584–4.514 0.3527
Invasion of dermis
 No dermal invasion 28.95% Reference Reference Reference
 Micro-invasion 20.00% 0.695 0.154–3.137 0.6362
 Deep dermal invasion 85.71% 5.167 1.876–14.230 0.0015
Metastasis status
 Without metastasis 27.08% Reference Reference Reference
 Metastatic diseases 85.71% 4.513 1.683–12.103 0.0028
Recurrence (N=51)
 No recurrence 27.91% Reference Reference Reference
 With recurrence 62.50% 2.587 0.907–7.382 0.0756
Concurrent malignancy
 No concurrent malignancy 29.41% Reference Reference Reference
 Adnexal carcinoma 33.33% 1.180 0.151–9.225 0.8744
 Internal malignancy 44.44% 1.595 0.629–4.044 0.3249
Types of treatment
 With surgical excision 31.91% Reference Reference Reference
 Without surgical excision 50.00% 1.642 0.544–4.950 0.3787
Margin status (N=47)
 Margin not free 33.33% Reference Reference Reference
 Margin free 31.03% 0.911 0.324–2.561 0.8596
Intraepithelial lesion (N= 31)
 Margin not free 37.50% Reference Reference Reference
 Margin free 21.74% 0.528 0.126–2.211 0.3822
  1. Abbreviation: CI confidence interval, Sub-HR sub-hazard ratio
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World Journal of Surgical Oncology

ISSN: 1477-7819

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