Fig. 1

Characterization of hypoxia risk score to predict prognosis of PAC. a Protein–protein interactions among 200 hypoxia-associated genes. b The 50 genes with the highest interaction degrees were extracted. c Sixteen hypoxia genes associated with patient’ OS were confirmed by univariate Cox regression. d Four hypoxia-related genes were chosen to establish a hypoxia risk model by multivariate Cox regression. e, f Spearman correlation analysis of four hypoxia genes in the TCGA and GEO databases