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Table 4 Univariate and multivariate Cox analysis of clinical characteristics on three sets

From: Comprehensive analyses of correlation and survival reveal informative lncRNA prognostic signatures in colon cancer

Variables Univariate Multivariate
  HR (95% CI for HR) p value Coef z p
Training set
Age 1 (1–1.1) 0.016 0.0442637 3.290 0.0010
Gender 0.92 (0.54–1.6) 0.75 0.0004572 0.002 0.9987
Tumor stage 2.2 (1.6–3) 3.3e −07 0.4570372 1.739 0.0820
Tumor invasion (T) 2.9 (1.8–4.8) 1.8e-05 0.6198692 1.871 0.0614
Lymph node (N) 2.2 (1.6–2.9) 9.5e −07 0.2121219 0.860 0.3895
Metastasis (M) 1.7 (1.2–2.3) 0.001 0.2204375 1.065 0.2869
Risk score 2 (1.6–2.6) 6.4e −08 0.6528934 4.518 6.24e −06
Testing set
Age 1 (0.98–1) 0.82 0.02209 1.359 0.17421
Gender 0.76 (0.36–1.6) 0.49 −0.19816 −0.454 0.65005
Tumor stage 2.8 (1.7–4.7) 6.2e −05 0.94479 2.720 0.00653
Tumor invasion (T) 1.8 (0.86–3.8) 0.12 −0.10185 −0.203 0.83914
Lymph node (N) 2.1 (1.3–3.4) 0.0034 −0.10574 −0.287 0.77424
Metastasis (M) 1.6 (1–2.5) 0.031 0.51952 1.630 0.10307
Risk score 1.4 (1–1.8) 0.027 0.34615 2.071 0.03837
Total set
Age 1 (1–1) 0.041 0.03938 3.833 0.000127
Gender 0.89 (0.58–1.4) 0.6 −0.02656 −0.115 0.908684
Tumor stage 2.3 (1.8–2.9) 1.5e −10 0.59692 2.802 0.005076
Tumor invasion (T) 2.6 (1.7–4) 5e −06 0.45556 1.691 0.090824
Lymph node (N) 2.1 (1.6–2.7) 2.1e −08 0.08203 0.394 0.693225
Metastasis (M) 1.6 (1.3–2.1) 0.00012 0.31324 1.870 0.061471
Risk score 1.6 (1.4–2) 2.8e −08 0.49875 4.845 1.27e −06
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